Questions and AnswersProf. Dr. Klaus Schughart

"I especially like the News section. It provides a very informative and up-to-date overview about important new discoveries in the field. The Perspectives section is extremely useful to get a general overview and relevant literature references upon a research field which is related to my research but which is not very familiar to me. Also, the Graphics are very useful!"

Selected Publications

B. Srivastava, P.Blazejewska, M. Heßmann, D. Bruder, R. Geffers, S. Mauel, A. D. Gruber, K. Schughart. (2009) Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections. PLoSONE, 4, e4857. doi:10.1371/journal.pone.0004857

K. Schughart and G. Churchill (2007) 6th Annual Meeting of the Complex Trait Consortium. Mammalian Genome, 18, 683-685. doi:10.1007/s00335-007-9057-x

J. Streicher, M.A. Donat, B. Strauss, R. Sporle, K. Schughart, G.B. Mueller (2000) Computer-based three-dimensional visualization of developmental gene expression. Nature Genetics 25,147-52. doi:10.1038/75989

Hrabé de Angelis M., Flaswinkel H., Fuchs H., Rathkolb B., Soewarto D., Marschall S., Heffner S., Pargent W., Wuensch K., Jung M., Reis A., Richter T., Alessandrini F., Jakob T., Fuchs E., Kolb H., Kremmer E., Behrendt H., Ring J., Zimmer A., Pfeffer K., Schughart K., Wolf E., and Balling R. (2000) Genome wide large scale production of mutant mice by ENU mutagenesis. Nature Genetics 25, 444-447. doi:10.1038/78146

K. Schughart, R. Bischoff, D. Ali Hadji, O. Boussif, F. Perraud, N. Accart, U.B. Rasmussen, A. Pavirani, N. van Rooijen, H.V.J. Kolbe (1999) Effect of liposome-encapsulated clodronate pretreatment on synthetic vector-mediated gene expression in vivo. Gene Therapy 6, 448-453. free full text

J. Favor, R. Sandulache, A. Neuhaeuser-Klaus, W. Pretsch, B. Chatterjee, E. Senft, W. Wurst, V. Blanquet, P. Grimes, R. Spoerle and K. Schughart (1996) The mouse Pax2/1Neu mutation is identical to a human PAX2 mutation in a family with renal-coloboma syndrome and results in developmental defects of the brain, ear, eye and kidney. Proc. Natl. Acad. Sci. USA 93, 13870-13875. free full text

R. Spoerle, T. Guenther, Struwe, M. and K. Schughart (1996) Severe defects in the formation of epaxial musculature in open brain (opb) mutant embryos. Development 122, 79-86. free full text

T. Guenther, M. Struwe, A. Aguzzi and K. Schughart (1994) Open brain, a new mouse mutant with severe neural tube defects shows altered gene expression patterns in the developing spinal cord. Development 120, 3119-3130. free full text

K. Schughart, C.J. Bieberich, R. Eid and F.H. Ruddle (1991) A regulatory region from the mouse Hox-2.2 promoter directs gene expression into developing limbs. Development 112, 807-811. free full text

J. Malicki, K. Schughart and W. McGinnis (1990) Mouse Hox-2.2 specifies thoracic segmental identity in Drosophila embryos and larvae. Cell 63, 961-967. doi:10.1016/0092-8674(90)90499-5

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