News

  • 16 May 2013 - ETH ZURICH/CELL HOST & MICROBE

    Proteome atlas for the tuberculosis pathogen

    Mycobacterium tuberculosis, tuberculosis, Proteomics

    Colorized scanning electron micrograph of Mycobacterium tuberculosis bacteria. Source: CDC/ R. Butler; J. Carr

    Researchers from ETH Zurich have mapped the coordinates for all the proteins of the tuberculosis pathogen Mycobacterium tuberculosis. Thanks to this "atlas", scientists are now able to easily find and accurately measure every protein of this bacterium that causes dangerous lung diseases. [ more ]

  • 15 May 2013 - PUBLIC LIBRARY OF SCIENCE/ PLOS MEDICINE

    Asymptomatic carriage of M. pneumoniae in children

    The bacterium Mycoplasma pneumoniae is carried at high rates in the upper respiratory tracts of healthy children and usual diagnostic tests cannot differentiate between such asymptomatic carriage and actual respiratory tract infection, according to a study by Dutch researchers published in this week's PLOS... [ more ]

  • 14 May 2013 - LANCET

    Four pathogens are causing most diarrhoeal deaths

    Escherichia coli, gastrointestinal infections, Shigella, rotavirus

    Transmission electron micrograph (TEM) of intact, double-shelled rotavirus particles.

    New research in The Lancet reports that just four pathogens--rotavirus, Cryptosporidium, enterotoxigenic Escherichia coli producing heat-stable toxin, and Shigella--are causing most cases of moderate-to-severe diarrhoea (MSD) among children living in the poorest countries of the world. [ more ]

  • 10 May 2013 - NIH/SCIENCE

    Bacteria make mosquitoes immune to malaria

    malaria, Plasmodium falciparum

    Anopheles stephensi - a malarial vector from Egypt to China. CDC/J. Gathany

    Scientists have established an inheritable bacterial infection in malaria-transmitting Anopheles mosquitoes that renders them immune to malaria parasites. Specifically, the scientists infected the mosquitoes with Wolbachia, a bacterium common among insects that previously has been shown to prevent malaria-inducing... [ more ]

  • 8 May 2013 - CELL PRESS/ BIOPHYSICAL JOURNAL

    New insights into Ebola infection

    Ebola

    Sequences from ancient relatives of Ebola viruses are found in the human genome. F. Murphy/CDC

    The Ebola virus is among the deadliest viruses on the planet, killing up to 90% of those infected, and there are no approved vaccines or effective therapies. A study published by Cell Press in the Biophysical Journal reveals how the most abundant protein making up the Ebola virus—viral protein 40 (VP40)—allows the... [ more ]

  • 7 May 2013 - BIOMED CENTRAL

    Anti-depressant link to Clostridium difficile infection

    Clostridium difficile

    Clostridium difficile colonies. CDC/Dr. G. Jones

    Certain types of anti-depressants have been linked to an increase in the risk of Clostridium difficile infection (CDI) finds a study in BioMed Central's open access journal BMC Medicine. Awareness of this link should improve identification and early treatment of CDI. [ more ]

  • 5 May 2013 - MASSACHUSETTS GENERAL HOSPITAL /NATURE

    Rapid diagnosis of infections with portable device

    DNA is amplified in the chambers on the left. TB-specific sequences are magnetically labeled in the microfluidic mixing channels in the center and detected by passage through the micro-NMR coil on...

    A handheld diagnostic device that Massachusetts General Hospital (MGH) investigators first developed to diagnose cancer has been adapted to rapidly diagnose tuberculosis (TB) and other important infectious bacteria. Two papers appearing in the journals Nature Communications and Nature Nanotechnology describe portable... [ more ]

  • 30 April 2013 - WILEY

    Targeting prescribers can reduce use of antibiotics

    Colorized scanning electron micrograph of methicillin-resistant Staphylococcus aureus (MRSA) bacteria. Source: J. Haney, CDC

    Giving prescribers access to education and advice or imposing restrictions on use can curb overuse or inappropriate use of antibiotics in hospitals, according to a new Cochrane systematic review. This is important because unnecessary use of these life-saving drugs is a key source of antibiotic resistance in bacteria. [ more ]

  • 25 April 2013 - SCIENCE CHINA PRESS

    Source identification of H7N9 influenza virus

    H7N9, H9N2, H7N3, bird flu

    Influenza A virions. Source: CDC/ F. A. Murphy

    In March 2013, a novel H7N9 influenza virus was identified in China as the etiological agent of a flu-like disease in humans, resulting in some deaths. A group of scientists, led by Professor Chen Hualan have investigated the origins of this novel H7N9 influenza virus (Shi et al., 2013). Following analysis of H7N9... [ more ]

  • 24 April 2013 - UNIVERSITY OF EXETER/PLOS BIOLOGY

    Battling with bugs to prevent antibiotic resistance

    Escherichia coli, antibiotic resistance

    Colorized scanning electron micrograph of Escherichia coli bacteria. Source: Janice Haney Carr / CDC

    New scientific research published in the journal PLoS Biology shows that bacteria can evolve resistance more quickly when stronger antibiotics are used. Researchers from the University of Exeter and Kiel University in Germany treated Escherichia coli with different combinations of antibiotics in laboratory... [ more ]

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Newsletter

DZIF (German Centre for Infection Research) Logo

German Centre for Infection Research

United against Infections

It is the 21st century and infections are still a major challenge for medicine. What is our recourse as germs become increasingly resistant to antibiotics? What can we do to prevent the spread of a pathogen? The researchers at the German Centre for Infection Research (Deutsches Zentrum für Infektionsforschung, DZIF) are tackling these and many other issues.