Perspectives

Perspectives contains in depth articles on key topics in infection research.

31 March 2008 R. John Davenport

Front Lines: Africa faces unique challenges in the fight against infectious diseases

 
Infectious diseases pose a serious threat for Africa`s future
Infectious diseases pose a serious threat for Africa`s future © Andreas Lengeling

Despite profound medical advances over the last century, infectious diseases still present a serious threat to world health. And though many regions are hard-hit, perhaps no part of the world faces as extreme challenges as Africa does. Ongoing fights against HIV, tuberculosis, and malaria, coupled with changing demographics, modernizing cities, and bloody conflicts, present a difficult road ahead for African nations to keep people healthy.

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01 February 2008 R. John Davenport

Coming to a Boil: Climate change encourages the expansion of infectious disease

Will there be a triumphant progress of infection diseases while heating up our climate?

 
An evening in the area of the former Larsen-B-Iceshelf and the Antarctic peninsula.
An evening in the area of the former Larsen-B-Iceshelf and the Antarctic peninsula. © Gauthier Chapelle, AWI

“Whoever wishes to investigate medicine properly, should proceed thus: in the first place to consider the seasons of the year, and what effects each of them produces for they are not at all alike, but differ much from themselves in regard to their changes.” So wrote the Greek physician Hippocrates in 400 BC, imploring physicians to heed the effects of weather and climate on disease. Now, as global climate change threatens to alter life as we know it, the effect of climate on health, including infectious diseases, returns to the fore.

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10 December 2007 R. John Davenport

Vaccine Development: Promise and Peril

High hopes and deap disappointments go along with vaccine development

 
Promise and peril standing back to back in vaccine development © stock-xchange / Brian Hoskins
Promise and peril standing back to back in vaccine development © stock-xchange / Brian Hoskins

Vaccines have suppressed many scourges over the last two centuries and new vaccines could aid the fight against numerous current health threats. Yet, counterbalancing successful vaccine development are expectations and disappointments.

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09 October 2007 R. John Davenport

A shifting threat

Development of antibiotic resistance and spread outside of hospitals weighs on researchers’ efforts to tame Staphylococcus

 
Bacterial cells of Staphylococcus aureus. © Eric Erbe, Christopher Pooley, Beltsville Agricultural Research Center
Bacterial cells of Staphylococcus aureus. © Eric Erbe, Christopher Pooley, Beltsville Agricultural Research Center

Otherwise-healthy children die of unusual infections. Antibiotic-resistant bacteria spread through sports teams. And the last line drug loses effectiveness. The threat of Staphylococcus to human health continues, and presents new challenges for doctors and scientists. Researchers are delving into developing new antibiotics, understanding why staph infections aren’t restricted to hospitals anymore, and figuring out how the bug evades the host immune system.

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01 September 2007 R. John Davenport

A new century of new challenges

Infection Research faces new threats

 
The (re-)emergence of old and new infectious diseases is plaguing the world and might bring it out of balance. Arnold Böcklin, ‘Die Pest’ (The Plague), 1898.
The (re-)emergence of old and new infectious diseases is plaguing the world and might bring it out of balance. Arnold Böcklin, ‘Die Pest’ (The Plague), 1898.

Infection research is experiencing something of a rebirth. The century-long decline in rates of infectious diseases has flattened out and in some cases risen over the last two decades. Many diseases that were once well-controlled have remounted their attack, and a host of new sicknesses have come to the fore. In addition, the body of scientific data has provided a crystal ball through which scientists conjure future diseases - though researchers don't when or if these new scourges will appear and how devastating they will be.

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